The museum accommodates a comprehensive collection of sacral art from the 10th to the 20th Century. This comprises approximately 6,000 exhibits in the exhibition rooms, which from 1991 to 1993 underwent complete renovation. An outstandingly beautiful exhibit is the Madonna belonging to Bishop Imad of Paderborn (1051/1058), which is one of the oldest depictions of the Madonna on the Throne in occidental art. The remarkable collection of sculptures comprises medieval themes and excellent examples of Westphalian sculptures in the Baroque style, like the 1736 festive Libori Altar.
The Cathedral's Treasury, in the medieval vault of the former Bishop's Palace, contains liturgical instruments, relics and other creations of clerical art treasure.
To round of its broad spectrum, the Diocesan Museum offers themed exhibitions on a regular basis.